This system includes:
- VF-P10-A Vanquish Binary Pump F
- VF-A10-A Vanquish Split Sampler FT
- VH-C10-A Vanquish Column Compartment H
- VF-D40-A Vanquish Variable Wavelength Detector F
- PC with data
The Thermo Scientific Vanquish Flex UHPLC system is biocompatible with a state-of-the-art binary high-pressure pump and state-of-the-art binary solvent blending. This ultra high performance liquid chromatography system shares all Vanquish values, such as a design focused on uptime, robustness and reliability. Multiple detection options as well as Thermo Scientific Viper fingertight connections throughout the system will give you the performance you need with the ease of use you want. The SmartFlow pumping technology with automatic compensation for changing eluent compressibility ensures excellent flow and gradient precision, independent of eluent composition and backpressures. This gives you unrivaled retention time precision and highest data confidence, even for ternary and quaternary gradients, and for more freedom in method development and application switching. Detection capabilities include high sensitivity and linearity Diode Array Detection with LightPipe technology, selective and sensitive Fluorescence Detection and near-universal detection capabilities with the Vanquish Charged Aerosol Detector.
Key Features:
- Integrated modularity design concept to offer uncompromising UHPLC
- State-of-the-art quaternary solvent blending 1000 bar of pump pressure and flow rates up to 8 mL/min
- Industry-leading flow and gradient precision
- Multiple detection options including DAD, FLD and CAD
For analyses that require more flexibility to accommodate all applications, Thermo Scientific Vanquish Flex UHPLC systems enable you to increase your productivity and drive innovation without compromising quality. Whether you need an LC or LC-MS solution, the flexibility of the Vanquish Flex systems with binary or quaternary solvent blending provides the most advanced performance through better separations, more results and easier interaction. Like all members of our Vanquish product line, Vanquish Flex UHPLC systems offer hardware precision, detector sensitivity, and simplicity of operation.
| Category | Vanquish Flex UHPLC Systems |
| System pressure, maximum | 1000 bar |
| Flow range, maximum | 0–8 mL/min |
| Pump options (default gradient delay volume) | Binary (200 µL) |
| Biocompatibility | Yes |
| pH range | 2–12, chloride concentration up to 1 mol/L |
| System design | Modular |
| Touchscreen user interface display compatible (optional) | Yes |
| Solvent monitoring system compatible (optional) | Yes |
| Customizable gradient delay volume to simplify method transfer | Yes, with metering device |
| SmartInject technology for maximum injection precision and improved column lifetime | Yes |
| Injection volume range | Standard: 0.01 – 25 µL
Optional: 0.01 – 100 µL |
| Sample cooling | 4-40°C |
| Sample capacity (standard)
Based on standard 12 mm OD vials (≤1.5 mL) |
4 racks of 54 vials (≤ 1.5 mL) each, other rack formats available
+ capacity of 12 × 22.5 mm OD vials (≤10 mL) in the carousel |
| Sampler extension available (optional) | Yes, with Vanquish Charger |
| Column compartment thermostatting | Yes, 5-120°C Still air and forced air |
| Column compartment pre-heater | Active and passive |
| Column compartment post-column cooler | Yes |


